Education

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Employment History

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Teaching

2006- Interim Associate Dean for Preclinical Education, Touro University College of Osteopathic Medicine, Las Vegas, NV
2004-Associate Professor, Touro University College of Osteopathic Medicine, Las Vegas, NV- Neuroscience

1999-2002: Professor and Chairman, Dept. of Biomechanics and Bioengineering, New York College of Osteopathic Medicine, Old Westbury, N.Y- Biomechanics
1995- 2001: Associate Professor, Dept. of Neuroscience, New York College of Osteopathic Medicine, Old Westbury, N.Y
1990-1993: Research Assistant Professor, Dept. of Neurology, SUNY, Stony Brook, N.Y.
1989-1991: Associate Professor, Dept. of Neuroscience, New York College of Osteopathic Medicine, Old Westbury, N.Y.
1988-1989: Adjunct Associate Professor, Uniformed Services University of the Health Sciences, Washington, D.C.
1981-1989: Research Assistant Professor, Dept. of Physiology, George Washington University.

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Honors & Awards

2005 Teacher of the Year Award, Touro College of Osteopathic Medicine, Nevada.
1998, 1999:George W. Northrop Medical Writing Award, American Osteopathic Association
1984,1985: Superior performance Award, Veterans Administration.
1973: High Honors in Chemistry, University of Florida.

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Publications

1.Burns, D.K. and Wells, M.R. The effect of muscle energy technique on gross range of motion in the cervical spine in asymptomatic subjects. J. Am. Osteopath. Assoc. 106: 137-142. (2006).
2.Rivera-Martinez,S. Wells, M. R., and Capobianco, J.D. A retrospective study of cranial strain patterns in patients with idiopathic Parkinson's disease. J. Am. Osteopath Assoc. 2002 102: 417-22. (2002).
3.Wells, M.R. Biomechanics: An Osteopathic Perspective. In “Foundations for Osteopathic Medicine” 2nd Edition, Lippincott , Willaims &Wilkins Philadelphia . p 63-89. (2002).
4.Scandalis, T.A., Bosak, A., Berliner, J.C., Helman, L.L., and Wells, M.R. Resistance training and gait function in patients with Parkinson’s disease. Am. J. Phys. Med. Rehabil. 80: 38-43 (2001).
5.Wells, M.R., Vaidya, U., Ricci, J.L. and Christie, C. A neuromuscular platform to extract motor signal information from lesioned nerves. A Technical Note. J. Rehab. Res. Dev. 38: 385-390. (2001).
6.Hallas, B.H. and Wells, M.R. A Novel Technique for Multiple Injections into the Mammalian Optic Nerve. Kopf Carrier (online) 54: (2001).
7.Wells, M. R., Giantinoto, S., D'Agate,D., Areman, R.D., Fazzini, E. A., Dowling, D., A. Bosak, B.S. Osteopathic manipulative treatment acutely improves functional gait performance in patients with Parkinson’s disease. JAOA 99: 92-98 (1999)
8.Kraus, K.H., Welch, J.A., Levy, W.J., Gugino, V.D., Wells, M.R. Motor evoked potentials in partially regenerated rat sciatic nerve suggest central nervous system plastic changes. Exp. Neurol. 143: 18-24. (1997)
9.Hallas, B., Lehman, S., Bosak, A. Tierney, S., Galler, R., Jacovina, P., Scandalis, T. and Wells, M. Behavioral Parameters for the Evaluation of Osteopathic Manipulation Therapy in a Rat Model of Arthritis. JAOA 97: 207-214 (1997).
10.Wells, M. R., Kraus,K., Batter, D.K., Blunt, D.G., Weremowitz ,J., Lynch,S. E., Antoniades H.N. and Hansson, .H.-A.Gel matrix vehicles for growth factor application in nerve gap injuries repaired with tubes: A comparison of Biomatrix, collagen and methylcellulose. Exp. Neurol. 146: 395-402 (1997).
11.Welch, J.A. Kraus, K.H., Wells, M.R., Blunt, D.G., Weremowitz, J. Effect of combined administration of insulin-like growth factor and platelet-derived growth factor on the regeneration of transected and anastomosed sciatic nerve in rat. Am J. Vet. Res. 58: 1033-1037 (1997).
12.Strasberg S.R., Watanabe O., Mackinnon S.E., Tarasidis G., Hertl M.C., Wells, M.R. Wire mesh as a post-operative physiotherapy assistive device following peripheral nerve graft repair in the rat. J Peripher Nerv Syst .1:73-6 (1996).
13.Duncan, I.D., Nadon, N.L., Hoffman, R.L., Lunn, K.F., Csiza, C., and Wells, M.R. Oligodendrocyte survival and function in the long lived strain of the myelin deficient rat. J. Neurocytol. 24: 745-762 (1995).
14.Wells, M.R., Vaidya, U. and Schwartz, J.P. Bilateral phasic increases in dorsal root ganglia nerve growth factor after unilateral sciatic nerve crush. Exp. Brain Res. 101: 53-58 (1994).
15.Wells, M.R. and Vaidya, U. RNA Transcription in Axotomized Dorsal Root Ganglion Neurons. Molec. Brain Res. 27: 163-166 (1994).
16.Vaidya, U. and Wells, M.R. Fetal spinal cord overlays: Incorporation and differentiation in adult host spinal cord. Internat. J. Neurol. 23-24 165-178 (1993)
17.Wells, M.R., Racis, S. P. and Vaidya, U. Changes in plasma cytokines associated with peripheral nerve injury. J. Neuroimmunol. 39: 261-268 (1992).
18.Zanakis, M.F., Hallas, B., Cebelenski, R., Yoon, H.S. and Wells, M.R. Construction of a microelectrode probe device for interfacing with the nervous system. Kopf Carrier No. 33: 1-6. (1992).
19.Diehl, A. M., Wells, M.R., Thorgeirsson, S.S., Brown, N., and Steer, C.J. Effect of Ethanol on polyamine synthesis during liver regeneration in rats. J. Clin. Invest. 85: 385-390. (1990).
20.Wells, M.R., and Vaidya, U. Morphological alterations in dorsal root ganglion neurons after peripheral axon injury: Association with changes in metabolism. Exp. Neurol. 104: 32-38. (1989).
21.Vaidya, U. and Wells, M.R. Cross-Species grafting and cell culture of Rhesus monkey fetal spinal cord and cerebral cortex. Prog. Brain Res. 78: 115-123 (1988).
22.Wells, M.R., Changes of ornithine decarboxylase activity in dorsal root ganglion cells after axon injury: Possible relationship to changes in chromatin structure. Exp. Neurol. 95: 313-0322. (1987).
23.Powel, A.M., Wells, M.R., Timmers, K.I. and Recant, L., Autoradiographic localization of [3H]-guanidinoethylmercaptosuccinic acid binding sites in rat islets of Langerhans. Life Sci. 40: 2511-2513. (1987).
24.Timmers, K.I., Voyles, N.R., King, C., Wells, M., Fartile, R. and Recant, L. Opioid peptides in rat islets of Langerhans. Immunoreactive Met- and Leu-Enkephalins and BAM-22P. Diabetes 35: 52-57. (1986).
25.Wells, M.R. Autoradiographic measurement of relative changes in ornithine decarboxylase in axotomized superior cervical ganglion neurons. Exp. Neurol. 92: 445-450. (1986).
26.Timmers, K., Voyles, N.R., King, C., Wells, M., Fartile, R. and Recant, L. Rat islet endocrine cells contain Met- and leu-enkephalins in high and low-molecular-weight forms. In "Neural and endocrine peptides and receptors" (Fifth International George Washington University Spring Symposium). T. Moody, Ed., Plenum Press, (1986). pp. 581-598.
27. Patel, U., Wells, M.R. and Freed, W.J. The dissociation and survival of rat and monkey adrenal chromaffin cells transplanted into rat brain. Cell and Tissue Res. 240: 281-285. (1985).
28.Wells, M.R. and Hall, M.F. Neuronal chromatin changes in layer V pyramidal cells of somatomotor cortex after pyramidal tract lesions as demonstrated b y [3H] actinomycin D binding. Exp. Neurol. 87: 393-402. (1985).
29.Wells, M.R. and Bernstein, J.J. Scar formation and the barrier hypothesis in the failure of mammalian CNS regeneration. In "Trauma of the Central Nervous System" (R. G. Dacey, Jr. et al. Eds.) Raven Press, New York. pp. 245-257. (1985).
30.Recant, L., Voyles, N.R., Timmers, K.I., Awoke, S., Bhathena, S.J. and Wells, M.R. Tissue opiate levels in hyper-and hypo-insulinemic animal models. Proceedings of Symposium on Opiate Peptides in the Periphery. Elsevier Publishing, N.Y. pp. 271-281. (1985).
31.Thadani, P.V. and Wells, M.R. Histofluorescent evaluation of the development of sympathetic nerve fibers in hearts of rats exposed to ethanol. Neuropharmacology 23: 1075-1079. (1984).
32.Wells, M.R. Alteration of [3H] actinomycin D binding to axotomized dorsal root ganglion cell nuclei: An autoradiographic method to detect changes in chromatin structure and RNA synthesis. Exp. Neurol. 86: 303-312. (1984).
33.Wells, M.R. Neurochemistry of synaptic renewal. In "Spinal Cord Reconstruction" (C.Kao, R. Bunge, and P. Reir, Eds.) pp. 197-208. (1983).
34.Bernstein, J.J., Ganchrow, D. and Wells, M.R. Spinal cord injury results in alteration of brain microcircuitry. In " Nervous System Regeneration" (A. Giuffrida-Stella, B. Haber, G. Hashim, J.R. Perez-Polo, Eds. ) Alan R. Liss, Inc., N.Y. pp. 197-208. (1983).
35.Bernstein, J.J. and Wells, M.R. [3H] lysine incorporation into protein of hemisected cycloheximide treated spinal cord. Exp. Neurol. 80: 549-560. (1983).
36. Wells, M.R. The devil, genetics, microenvironment and hope. Regeneration Research Newsletter (Veterans Administration) In 15-83-4: 3-6. (1983).
37.Wells, M.R. Chemical induction of central nervous system regeneration: its past and future. Paraplegia News 37: 26. (1983)
38.Wells, M.R. and Bernstein, J.J. Sonication enhanced histochemistry of wheat germ agglutinin binding to intracellular sites of rat layer V cortical neurons and spinal motoneurons. J. Neurosci. Res. 7: 253-266. (1982).
39.Wells, M.R. and Sprinkle, T.J. Purification of rat 2', 3'-cyclic nucleotide 3'-phosphodiesterase. J. Neurochem. 36: 633-639. (1981).
40.Bernstein, J.J., Ganchrow, D., and Wells, M.R. Neurochemistry of synaptic renewal. In "Plasticity in the Nervous System" (D.Fhlor and W. Precht, Eds.) pp. 75-86. (1981).
41.Wells, M.R., Lofton, S.A. and Bernstein, J.J. Influence of triiodothyronine on the amino acid uptake of brain and spinal cord in normal and spinal hemisected adult rats. J. Neurosci. Res. 6: 609-620. (1981).
42. Wells, M.R., Separation of radiolabelled protein from brain and spinal cord of spinal hemisected rats on SDS polyacrylamide slab gels. J. Neurosci. Res. 5: 51-62. (1980).
43.Wells, M.R. and Bernstein, J.J. Amino acid uptake in the spinal cord and brain of the long term spinal hemisected rat. Exp. Neurol. 68: 122-135. (1980).
44. Bernstein, J.J. and Wells, M.R. Puromycin induction of transient regeneration in mammalian spinal cord. Prog. Brain Res. 53: 21-38. (1980).
45. Sprinkle, T.J., Wells, M.R., Garver, F.A. and Smith, D.B. Studies on the Wolfgram high molecular weight CNS myelin proteins: Relationship to 2', 3'-cyclic nucleotide 3'-phosphodiesterase. J. Neurochem. 35: 1200-1208. (1980).
46.Bernstein, J.J., Wells, M.R., and Bernstein, M.E. Mammalian spinal cord regeneration: synaptic renewal and neurochemistry. In "Neuronal Plasticity" (C. Cotman, Ed. ) Raven Press, N.Y., pp. 49-71. (1978).
47. Bernstein, J.J., Bernstein, M.E., and Wells, M.R. Spinal cord regeneration in mammals: Neuroanatomical and neurochemical correlates of axonal sprouting. In " Physiology and Pathobiology of Axons: (S.G. Waxman, Ed.) Raven Press, N.Y. pp. 407-420. (1978).
48.Bernstein, J.J., Wells, M.R., and Bernstein, M.E. Effects of puromycin treatment on the regeneration of hemisected and transected rat spinal cord. J. Neurocytol. 7: 215-228 (1978).
49.Wells, M.R. and Bernstein, J.J. Amino acid incorporation into rat spinal cord and brain after simultaneous and interval sciatic nerve lesions. Brain Res. 139: 249-262. (1978).
50. Zanakis, M., Wells, M.R., and Bernstein, J.J. Incorporation of tritiated lysine into the brain and spinal cord of Cebus apella and Macacca mulata. J. Neurosci. Res. 3: 73-80. (1978).
51. Wells, M.R., Zanakis, M.F. and Bernstein, J.J. Blood-brain barrier disturbance and reconstitution after spinal cord hemisection in the rat. Exp. Neurol. 61: 214-218. (1978).
52.Bernstein, J.J., Wells, M.R. and Zanakis, M.F. Effects of puromycin on incorporation of [3H] lysine into protein following hemisection of rat spinal cord. Exp. Neurol. 61: 537-548. (1978).
53.Wells, M.R. Protein composition of spinal cord and cortex from short-term spinal hemisected rats. Exp. Neurol. 62: 708-719. (1978).
54.Bernstein, J.J. and Wells, M.R. Amino acid incorporation alteration in medulla, pons, midbrain, and cortex following spinal cord hemisection in the Cebus monkey (Cebus apella). Brain Res. 112: 475-483. (1977).
55.Wells, M.R. and Bernstein, J.J. Amino acid uptake in the spinal cord and brain of the short term spinal hemisected rat. Exp. Neurol. 57: 900-912. (1977).
56. Wells, M. R. and Bernstein, J.J. Early changes in protein synthesis following spinal cord hemisection in the Cebus monkey (Cebus apella). Brain Res. 111: 31-40. (1976).
57. Bernstein, J.J., Wells, M.R. and Bernstein, M.E. Dendrites and neuroglia following hemisection of rat spinal cord: Effects of puromycin. Adv. Neurol. 12: 437-451 (1975).

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Research Grants

2002-2005: Co- Investigator “A Mechanical/Neural Limb Prosthetic Interface” National Institutes of Health STTR
1998-2001: Principal Investigator, “ Efficacy of a Neural Interface for Potential Use in Limb Prosthetics” National Science Foundation.
1999-2001: Co-Investigator, "Effects of Osteopathic Manipulative Therapy on Locomotor Ability after Neocortical Injury in Rats." American Osteopathic Association
1998-1999: Co-Investigator, “Osteopathic Manipulation therapy in the Treatment of Parkinson’s Disease” American Osteopathic Association
1998-1999: Co-Investigator, “An Animal model for quantitative evaluation of osteopathic manipulation in adjuvant induced arthritis” American Osteopathic Association” - ( renewal)
1998-1999: Co-Investigator, “ The Effect of OMT on Range of Motion in the Arthritic Knee” American Osteopathic Association ”( renewal)
1996-1997: Co-Investigator, “ The Effect of OMT on Range of Motion in the Arthritic Knee” American Osteopathic Association” (pilot project )
1995-1996: Co-Investigator, “An Animal model for quantitative evaluation of osteopathic manipulation in adjuvant induced arthritis” American Osteopathic Association”
1993-1994: Co- Investigator, “ Development of an Animal Model to Detect the efficacy and Beneficial Effects of Manipulative Therapy on Joint Inflammation” American Osteopathic Association”
1989-1993: Principal Investigator, "Neuronal Interaction with Cell Environment in CNS and PNS Regeneration" Veterans Administration.
1985-1988: Principal Investigator, "The Neuronal Nuclear Response in Nervous System Regeneration" Veterans Administration,
1982-1984: Principal Investigator, "The Neuronal Nuclear Response in Nervous System Regeneration" Veterans Administration.

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