PUBLICATIONS 2008-2009
1. Baginsky, P. Should we treat all patients with coronary heart disease or the equivalent with statins? Current Atherosclerosis Reports 11: 28-35, 2009.
2. Cai, L., Balogh E., and M. Gochin. Stable extended human immunodeficiency virus type 1 gp41 coiled coil as an effective target in an assay for high-affinity fusion inhibitors. Antimicrob Agents Chemother, 2009. 53(6): p. 2444-9.
3. Balogh E, Wu D, Zhou G, Gochin M. NMR Second Site Screening for Structure Determination of Ligands Bound in the Hydrophobic Pocket of HIV-1 gp41. J Am Chem Soc. 2009 Feb 10; [Epub ahead of print]. PMID: 19206471
4. Licciardone JC, Clearfield MB, Guillory VJ. Clinical Practice Characteristics of Osteopathic and Allopathic Primary Care Physicians at Academic Health Centers: Results from the National Ambulatory Medical Care Survey. Academic Medicine 2009; 84:744-750.
5. Shah BM, Kemp R, Clearfield M. Using statins to treat ‘healthy’ patients: are we there yet? Expert Review of Pharmacoeconomics and Outcomes Research. 2009;9(2): 103-105.
6. Clearfield M. Clinical Trials Reports (ENHANCE, CORONA, CTT-Diabetes) Current Atherosclerosis Reports 2009; 11 (1): 3-8.
7. Foy, J.E. “Specialty College Liaison Activities with Colleges of Osteopathic Medicine” eJournal of the American College of Osteopathic Pediatricians. Vol. 1 No. 4, Medical Education: p. 1-5, August 2009.
8. Gochin, M. and L. Cai. The role of amphiphilicity and negative charge in glycoprotein 41 interactions in the hydrophobic pocket. J Med Chem, 2009. 52(14): p. 4338-44.
9. Gugliucci A, Kotani K, Taing J, Matsuoka Y, Sano Y, Yoshimura M, Egawa K, Horikawa C, Kitagawa Y, Kiso Y, Kimura S, Sakane N. Short-Term Low Calorie Diet Intervention Reduces Serum Advanced Glycation End Products in Healthy Overweight or Obese Adults. Ann Nutr Metab, 2009. 54(3): p. 197-201.
10. Gugliucci A. Bastos DH, Schulze J, Souza MF. Caffeic and chlorogenic acids in Ilex paraguariensis extracts are the main inhibitors of AGE generation by methylglyoxal in model proteins. Fitoterapia, 2009 80(6). p. 339-44.
11. Gugliucci, A. and D.H. Bastos. Chlorogenic acid protects paraoxonase 1 activity in high density lipoprotein from inactivation caused by physiological concentrations of hypochlorite. Fitoterapia, 2009. 80(2): p. 138-42.
12. Gugliucci A, Schulze J, Kinugasa E, Ogata H, Kimura S. The free fraction of paraoxonase 1 is not increased in patients with end stage renal disease undergoing hemodialysis. Clin Chim Acta, 2009. 402(1-2): p. 209-10.
13. Gugliucci A, K. Kotani, K. Tsuzaki, Y. Matsuoka, Y. Sano, M. Yoshimura, K. Egawa, C. Horikawa, Y. Kitagawa, Y. Kiso, T. Menini, J. Taing, N. Sakane. Changes on the physiological lactonase activity of serum paraoxonase 1 in healthy overweight and obese women after weight loss. J. Clin Biochem Nutrition. June 2009. [In press].
14. Yadong Cui, MD, PhD, Douglas J Watson, PhD, Cynthia J. Girman, DrPH, Deborah R. Shapiro, DrPH, Antonio M. Gotto, MD, DPhil, Hiserote Patricia DO, and Michael B. Clearfield, DO. Effects of Increasing High-Density Lipoprotein Cholesterol and Decreasing Low-Density Lipoprotein Cholesterol on the Incidence of First Acute Coronary Events (from the Air Force/Texas Coronary Atherosclerosis Prevention Study). The American Journal of Cardiology. doi: 10.1016/j.amjcard.200905.020
15. Hiserote PA, Clearfield M. Predicting Cardiometabolic Risk: The Evolution Continues Whole Patient Supplement to JAOA/DO 2009; 7(1): 7-9.
16. Gregorie CJ, Wiesen JL, Magner WJ, Lin AW, Tomasi TB. Restoration of immune response gene induction in trophoblast tumor cells associated with cellular senescence. J Reprod Immunol. 2009 Jul;81(1):25-33.
17. Barrows, B. Cheung, K. Bialobrzeski, T. Foster, Schulze J., Miller, A. Extracellular potassium dependency of block of HERG by quinidine and cisapride is primarily determined by the permeant ion and not by inactivation. Channels (Austin), 2009. 3(4).
18. Kimber L. Stanhope, Schwarz Jean-Marc, Nancy L. Keim, Steven C. Griffen, Andrew A. Bremer, James L. Graham, Bonnie Hatcher, Chad L. Cox, Artem Dyachenko, Wei Zhang, John P. McGahan, Anthony Seibert, Ronald M. Krauss, Sally Chiu, Ernst J. Schaefer, Masumi Ai, Seiko Otokozawa, Katsuyuki Nakajima, Takamitsu Nakan, Carine Beysen, Marc K. Hellerstein, Lars Berglund, and Peter J. Havel (2009). "Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans." J Clin Invest 119(5): 1322-34.
19. Mulligan, K., Khatami, H., Schwarz, J.M., Sakkas, G.K., DePaoli, A.M., Tai, V.W., Wen, M.J., Lee, G.A., Grunfeld, C., and Schambelan, M. 2009. The effects of recombinant human leptin on visceral fat, dyslipidemia, and insulin resistance in patients with human immunodeficiency virus-associated lipoatrophy and hypoleptinemia. J Clin Endocrinol Metab 94:1137-1144.
20. Clearfield M. Another Inconvenient Truth: Combining the Risks from Obesity and Metabolic Syndrome with Global Warming. Current Atherosclerosis Reports, 2008; 10:273-276.
21. Clearfield M. Consensus Report of the American Osteopathic Association, American College of Osteopathic Internists, American College of Osteopathic Family Physicians, American Academy of Physician Assistants and the Diabetes Consortium. Addressing Overweight and Obesity: Evolving to a Medical Consensus. J Am Osteopath Assoc. 2008; Suppl 1: 108:S2-S15.
22. Clearfield M. Clinical Trials Reports (SAGE, METEOR, ILLUSTRATE). Current Atherosclerosis Reports, 2008; 10(1):5-10.
23. Clearfield M. Cholesterol Treatment Trialists (CTT) Collaborators Efficacy of cholesterol lowering therapy in 18, 686 people with diabetes in 14 randomized trials of statins: a meta-analysis. Lancet 2008; 371:117-125.
24. Blitz NM, Eliot DJ (2008). Anatomical aspects of the gastrocnemius aponeurosis and its muscular bound portion – a cadaveric study. Part II. J. Foot Ankle Surg. 47(6):533-40.
25. Wiley, A. Edalat, K. Chiang, P. Mora, M. Mirro, K. Lee, M. Muhr, H. Elul, T. GSK-3beta and alpha-catenin binding regions of beta-catenin exert opposing effects on the terminal ventral optic axonal projection. Dev Dyn, 2008. 237(5): p. 1434-41.
26. A. Pelzer, M. Southard, A. Shah and Elul, T. The α-catenin and GSK3b binding regions of β-catenin shape optic axonal paths independent of the TCF/Left regulation domain. Presented at the AOA Research Convention, October 2008.
27. Foy, J.E. “Osteopathic Medical Student and Pediatric Resident Survey: Attitudes Towards COM Pediatric Medical Education and Osteopathic Specialty Societies”eJournal of the American College of Osteopathic Pediatricians Vol. 1, No. 1, Medical Education: p. 1-4, October 2008.
28. Hou, Y. and Gochin, M. Artificial ion channel biosensor in human immunodeficiency virus gp41 drug sensing. Anal Chem, 2008. 80(15): p. 5924-9.
29. Kazuhiko Kotani, Seiji Adachi, Kokoro Tsuzaki , Naoki Sakane and Gugliucci, A. The association between resistin, high-density lipoprotein cholesterol and carotid atherosclerosis in elderly women with hypertension. Int J Cardiol, 2008. doi:10.1016/j.ijcard.2008.11.066
30. Gugliucci, A. Hypochlorous acid is a potent inactivator of human plasminogen at concentrations secreted by activated granulocytes. Clin Chem Lab Med, 2008. 46(10): p. 1403-9.
31. Kazuhiko Kotani, Naoki Sakane, Gugliucci, Alejandro. The association between Trp64Arg polymorphisms of beta3-adrenergic receptor gene and systemic disorders: a possibility of prevention. Ann Clin Biochem 2008; 00:1. doi: 10. 1258/acb.2008.081282
32. Murakami, H., Bessinger, K., Hellmann, J. Luerman, G.C., Murakami S. (2008) Serotonin as a cause of behavioral aging in C. elegans. Neurobiology of Aging. 29(7):1093-100.
33. Kotani K, Kimura S, Tsuzaki K, Sakane N, Komada I, Schulze J, Gugliucci A. Reduced paraoxonase 1/arylesterase activity and its post-therapeutic increase in obstructive sleep apnea syndrome: a preliminary study. Clin Chim Act. 2008 Sep; 395 (1-2):184-5.
ABSTRACTS/POSTER PRESENTATIONS 2008-2009
1. Baginsky P. Close-ups - A Patient’s Perspective: A Battle to Overcome “Diabulimia”. Am Fam Physician 79: 263, 2009.
2. Baginsky P, A. Gugliucci. "Low Adiponectin Levels are Associated with Diabetes and Prediabetes Among Latino Subjects" Diabetes, 2009. Abstract No. 2246-PO.
3. Foy J.E., Hahn, K. “School Based Health Centers: A Four Year Experience, with a Focus on Reducing Student Exclusion Rates”. Osteopathic Medicine and Primary Care Vol. 3:3, 2009.
4. Gugliucci, A. (2009) More on the glycotoxin controversy: a link between dietary AGEs and hepatic fibrosis. IMARS Highlights 4; 2, 15.
5. Gugliucci, A. (2009) AGEs and RAGE in muscle: deleterious effects of weight parallel those of aging. IMARS Highlights 4; 2, 21.
6. Hermel E, K.D. Klapstein and M. Yavari. Presence of the functional Caspase-12 allele in Indian subpopulations. Immunology 2009, May 8-12, Seattle, WA.
7. Daniel Keppler, Jun Zhang, Teeru Bihani and Lin, Athena. Differential Expression of the Cysteine Protease Inhibitors CST1 & CST6 during Senescence. Gordon Research Conference, Ventura, CA. Feb 15-Feb 19 2009.
8. Ricther, K., Barrows, B., Schulze, J., and Miller, A. Activation of the cardiac potassium channel HERG may be a determinant of the extracellular potassium dependency of block of HERG by terfenadine. Presented by Kris Richter (OMSII) at the Leiden Medical Students Association Conference, Leiden, The Netherlands, March 09.
9. Ricther, K., Barrows, B., Hioe, S., Yun, J., Farrell, M., Schulze, J., and Miller, A. Block of the HERG mutant D540K by terfenadine shows the opposite dependency on extracellular potassium compared to block of WT HERG by terfenadine. Presented by A. Miller at the Biophysical Society Meeting, Boston, Ma, March 09.
10. Puder, Barbara. "Neuroscience teacher training program for elementary school teachers" American Association of Anatomists annual meeting, New Orleans, LA, April 2009.
11. Dyachenko A, K. Meszaros, J. Schulze, A. Gugliucci, J. Schwarz, S. Kimura. Elevated D-Lactate Concentrations in Serum and Urine of Diabetic Patients. JAOA. Vol. 108. No 8. August 2008.
12. Blitz NM, Eliot DJ (2008): Anatomical aspects of the gastrocnemius aponeurosis and its muscular bound portion – a cadaveric study. 25th meeting Amer. Assoc. Clinical Anatomists, p. 75.
13. Eliot DJ, Silverman B (2008): A final farewell. 25th meeting Amer. Assoc. Clinical Anatomists, p. 84.
14. Foy, J.E. and Hahn, K. “School-Based Health Centers and the Touro University College of Osteopathic Medicine”: A Collaboration” Abstract. JAOA 108: 453. August 2008.
15. Tang M., Cabanne M., Tiglao S., Elrod B., Dominguez K., and Garcia-Russell N. MEEDIG IX [Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases]. Irvine, California, USA, October 30th-November 1st 2008. Spontaneous Induction of Salmonella enterica serovar Typhimurium LT2 prophages.
16. Cabanne M., Tang M., Tiglao S., Elrod B., Dominguez K., and Garcia-Russell N. AOA Annual Research Conference. Las Vegas, Nevada, USA, October 26th 2008. The response of the Salmonella Typhimurium prophages to environmental stress.
17. Gugliucci A, J. Schulze. Hypochlorous acid (HOCI) is a potent inactivator of human proteins responsible for protection against thrombosis and LDL oxidation: a comparative study on plasinogen and paraoxonase 1. Third International Conference on Paraoxonases, September 7th-10th, 2008, Los Angeles, California.
18.Gugliucci A, K. Kotani, K., Tsuzaki, N. Sakane, I. Komada, J. Schulze, S. Kimura. Reduced paraoxonase 1 activity in sleep apnea-hypopnea patients: effects of 6 months treatment with continuous positive airway pressure treatment. A pilot study. Third International Conference on Paraoxonases, September 7th-10th, 2008, Los Angeles, California.
19.Gugliucci A, K. Kotani, S. Kimura, K. Tsuzaki, I. Komada, J. Schulze, N. Sakane. High levels of serum advanced glycation endproducts in patients with obstructive sleep apnea syndrome are reduced by continuous positive air pressure treatment. Society for Free Radical Biology Medicine 15th Annual Meeting, November 19-23, 2008, Indianapolis.
20. Gugliucci A, Bastos D. (2008) Glycation of lipoproteins: a minireview. IMARS Highlights 3;6, 2-13.
21. Keppler, D., Zhang, J., Bihani, T. and Lin, A.W. Specific upregulation of the cysteine protease inhibitor CST1 during senescence. Presented at the Keystone Symposium on “Metabolic Pathways of Longevity”, from March 30 to April 3, 2008 in Copper Mountain, Colorado.
22. Keppler, D., Zhang, J., Bihani, T. and Lin, A.W. The cysteine protease inhibitor CST1 is a candidate biomarker of senescent cells. Presented at the 89th Annual Meeting of the American Association for the Advancement of Science (AAAS) - Pacific Division, from June 15 to 20, 2008 in Waimea, Hawaii.
23. Marske C, Anderson R, Silverman B, and Eliot DJ (2008): Central-line placement “clinic,” a cadaver-based learning exercise. 25th meeting Amer. Assoc. Clinical Anatomists, p. 116.
24. Silverman B, Eliot DJ (2008): A novel approach to the anatomy of the pharynx and larynx. 25th meeting Amer. Assoc. Clinical Anatomists, p. 152.
25. D. Bastos, Schulze, J. Gugliucci A. In vitro anti-glycation effects of chlorogenic acid: preliminary results. 1st International Symposium on Mate and Health, October 16-17, Montevideo, Uruguay, October 2008. B20
26. D. Bastos, Schulze, J. Gugliucci A. Chlorogenic acid inhibits alpha-dicarbonyl glycation and peroxidation of human low density lipoprotein. International Symposium on Mate and Health. October 16-17, Montevideo, Uruguay. October 2008. B31.
27. D. Bastos, Schulze J, Gugliucci A. Chlorogenic acid protects paraoxonase 1 activity in high density lipoprotein from inactivation caused by chlorination. 1st International Symposium on Mate and Health, October 16-17, Montevideo, Uruguay. October 2008. B15.
28. Philbin N., Boesch, B., Muraoka N., McClymont M., Doxey, R., Ostrander, S., Ip, E., Wong, T. Performance of a Low or Moderate Intensity Exercise Bout Results in Equivalent Moderation of Glycemia After an Oral Glucose Load in Non-Diabetic Subjects. The Journal of the American Osteopathic Association, 108 (8) August 2008 (Poster Presentation: 52nd Annual AOA Research Conference (October 2008), Las Vegas, NV.
Book Publications
Gugliucci, A. and Thornburg, R. (2009) Biosynthesis and Degradation of Nucleotides. Medical Biochemistry, 3rd Ed. Mosby Elsevier. John W Baynes and Marek H Dominiczak (Ed.) ISBN: 978-0-323-05371-6 Ch. 30, pp. 403-412.
Thornburg, R. and Gugliucci A. (2009) Deoxyribonucleic Acid. Medical Biochemistry, 3rd Ed. Mosby Elsevier. John W Baynes and Marek H Dominiczak (Ed.) ISBN: 978-0-323-05371-6 Ch. 31, pp. 413-422.
Hartwig, WC. (2009) Med School Rx: Getting In, Getting Through and Getting On With Doctoring. New York: Kaplan Publishing, 325pp.
Updated as of 08/21/2009
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